IL4
Immune response
Cis-regulatory,
SNP
Homo sapiens
human - (species)
Intraspecific
Linkage Mapping
Rockman MV; Hahn MW; Soranzo N ; et al. (2003)
Positive selection on a human-specific transcription factor binding site regulating IL4 expression.
GP00000497
IL4
P05112
Physiology
_524T promoter single base-pair substitution affecting binding of the NFAT transcription factor
Homo sapiens
human - (species)
Homo sapiens
human - (species)
IL4
Homo sapiens
human - (species)
Published - Accepted by Curator
interleukin-4
Immune response
Cis-regulatory,
SNP
Homo sapiens
human - (species)
Interspecific
Candidate Gene
Rockman MV; Hahn MW; Soranzo N ; et al. (2003)
Positive selection on a human-specific transcription factor binding site regulating IL4 expression.
GP00000504
IL4R
P24394
Physiology
1bp substitution in promoter
Primates
(order)
Homo sapiens
human - (species)
interleukin-4
Homo sapiens
human - (species)
Published - Accepted by Curator
TLR6-TLR1-TLR10 cluster
Immune response
Unknown,
Complex Change
Homo sapiens
human - (species)
Intraspecific
Association Mapping
Laayouni H; Oosting M; Luisi P ; et al. (2014)
Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-li[...]
1 Additional References
GP00001130
TLR1
Q15399
Physiology
Several Complex Haplotypes under positive selection - evidence on Adaptive Introgression from Neanderthal (2 haplotypes) and Denisova (1 haplotype)
Homo sapiens
human - (species)
Homo sapiens
human - (species)
TLR6-TLR1-TLR10 cluster
Homo sapiens
human - (species)
Published - Accepted by Curator